Our Services

Mr. & Mrs. Fillers Aesthetics – Portsmouth’s Leading Aesthetic Clinic

Looking for the best aesthetic treatments in Portsmouth?

At Mr. & Mrs. Fillers Aesthetics, we specialise in advanced non-surgical treatments designed to rejuvenate, sculpt, and enhance — using the latest techniques and premium products. Explore our services below:

Anti-Ageing & Facial Rejuvenation Treatments

Dermal Fillers

Add volume, smooth deep lines, and enhance features with our expertly applied dermal fillers. Popular areas include lip filler, cheek filler, jawline sculpting, under-eye (tear trough), non-surgical chin enhancement and many more.

Anti-Wrinkle Injections

Reduce forehead lines, frown lines, and crow’s feet with anti-wrinkle injections and many more. A safe and effective way to achieve smoother, younger-looking skin at Portsmouth’s trusted clinic.

Polynucleotide Skin Rejuvenation

A cutting-edge regenerative skin treatment that improves elasticity, reduces wrinkles, and boosts collagen production. Ideal for under-eyes, full face, neck, and hands.

Skin Boosters (Profhilo, Seventy Hyal & More)

Injectable moisturisers that hydrate and firm the skin from within. Best for dull, crepey, or dehydrated skin, restoring a radiant, youthful glow.

Microneedling with or without PRP

Boost collagen, refine pores, and improve acne scarring. Our microneedling treatments can be combined with serums or PRP (Platelet-Rich Plasma) for enhanced skin rejuvenation.

Skin Health & Texture Improvement

Chemical Peels

Medical-grade peels to treat pigmentation, acne, fine lines, and uneven skin tone. Safe and effective for long-term skin improvement.

PRP Therapy (Vampire Facial)

Natural anti-ageing using your own plasma. Improves under-eye hollowness, skin texture, and even helps with hair regrowth.

Hair Fillers

Clinically proven hair rejuvenation treatment using peptides to strengthen follicles, promote hair growth, and reduce thinning.

Fat Reduction & Facial Contouring

Fat Dissolving Injections (Lemon Bottle & Aqualyx)

Say goodbye to stubborn pockets of fat in the chin, jawline, abdomen, or flanks. Our non-surgical fat dissolving treatments help contour and define — with visible, lasting results.

Temple Filler for Facial Lifting

Restore volume and lift the upper face with temple filler — often overlooked but key in non-surgical facelift strategies.

Lip Fillers
Looking for safe, natural-looking lip enhancement in Portsmouth?
At Mr. & Mrs. Fillers, we offer expert lip filler treatments using premium hyaluronic acid-based products for fuller, more defined lips.

Lip fillers are safe, non-surgical injections that add volume, shape, and structure to the lips for a plumper, more balanced look. They are used to effectively improve facial features, giving you a refreshed and youthful appearance.

Consultation: A consultation will take place to discuss your treatment goals and medical history.
Preparation: The treatment area is thoroughly disinfected. Numbing (cream) are used to provide maximum comfort during the treatment.
Injection: Once the area is prepared, the dermal filler is carefully injected beneath the skin using a fine needle or cannula. The injection process is relatively quick and usually well-tolerated. After the injections, the practitioner may massage the treated area to ensure the filler is evenly distributed. They will also assess the results and make any necessary adjustments to achieve the best result.
Post-treatment care: You may experience some mild swelling, redness, or bruising at the injection site. You will be provided with post-treatment care instructions to minimise any potential side effects and ensure the best results.
Follow-up: A follow-up can be arrange after 2 weeks to ensure best results.

Nasolabial folds/ Smile Lines/ Marionette Lines
Softening deep smile lines for a more youthful, refreshed look is easier than ever with nasolabial fold fillers at Mr. & Mrs. Fillers in Portsmouth.

Nasolabial folds — the lines that run from the sides of your nose to the corners of your mouth — can become deeper with age.
Dermal fillers made from hyaluronic acid are used to gently lift and smooth these folds, restoring volume and softening their appearance without surgery.

Consultation: A consultation will take place to discuss your treatment goals and medical history.
Preparation: The treatment area is thoroughly disinfected. Numbing (cream) are used to provide maximum comfort during the treatment.
Injection: Once the area is prepared, the dermal filler is carefully injected beneath the skin using a fine needle or cannula. The injection process is relatively quick and usually well-tolerated. After the injections, the practitioner may massage the treated area to ensure the filler is evenly distributed. They will also assess the results and make any necessary adjustments to achieve the best result.
Post-treatment care: You may experience some mild swelling, redness, or bruising at the injection site. You will be provided with post-treatment care instructions to minimise any potential side effects and ensure the best results.
Follow-up: A follow-up can be arrange after 2 weeks to ensure best results.

Tear Through Filler
Tired, hollow under-eyes? At Mr. & Mrs. Fillers in Portsmouth, we offer expert tear trough filler treatments to brighten and refresh your under-eye area, reducing dark circles and tired-looking hollows without surgery.

Tear trough fillers use hyaluronic acid-based dermal filler to gently add volume under the eyes. This treatment is used to address the hollowness, dark shadows, and the appearance of fatigue, leaving you with a smoother, more awake look.

The "tear trough" refers to the area between the lower eyelid and the upper cheek.

Consultation: A consultation will take place to discuss your treatment goals and medical history.
Preparation: The treatment area is thoroughly disinfected. Numbing (cream) are used to provide maximum comfort during the treatment.
Injection: Once the area is prepared, the dermal filler is carefully injected beneath the skin using a fine needle or cannula. The injection process is relatively quick and usually well-tolerated. After the injections, the practitioner may massage the treated area to ensure the filler is evenly distributed. They will also assess the results and make any necessary adjustments to achieve the best result.
Post-treatment care: You may experience some mild swelling, redness, or bruising at the injection site. You will be provided with post-treatment care instructions to minimise any potential side effects and ensure the best results.
Follow-up: A follow-up can be arrange after 2 weeks to ensure best results.

Cheek Filler
Enhance your natural features with expertly applied cheek filler at Mr. & Mrs. Fillers in Portsmouth. This popular treatment adds lift, volume, and definition to the mid-face — helping you achieve a youthful, sculpted appearance without surgery.

Cheek fillers are hyaluronic acid-based dermal fillers used to restore lost volume, contour the cheekbones, and improve overall facial balance. They’re ideal for lifting the mid-face and reducing the appearance of sagging or tired skin.

Consultation: A consultation will take place to discuss your treatment goals and medical history.
Preparation: The treatment area is thoroughly disinfected. Numbing (cream) are used to provide maximum comfort during the treatment.
Injection: Once the area is prepared, the dermal filler is carefully injected beneath the skin using a fine needle or cannula. The injection process is relatively quick and usually well-tolerated. After the injections, the practitioner may massage the treated area to ensure the filler is evenly distributed. They will also assess the results and make any necessary adjustments to achieve the best result.
Post-treatment care: You may experience some mild swelling, redness, or bruising at the injection site. You will be provided with post-treatment care instructions to minimise any potential side effects and ensure the best results.
Follow-up: A follow-up can be arrange after 2 weeks to ensure best results.

Jawline Filler
Define and sculpt your profile with jawline filler at Mr. & Mrs. Fillers in Portsmouth. This non-surgical treatment enhances the structure of your lower face for a sharper, more contoured appearance with natural-looking results.

Jawline filler is a hyaluronic acid-based dermal filler treatment used to add definition, structure, and symmetry to the lower face. It can sharpen the jawline, improve facial balance, and even reduce the appearance of jowls.

Consultation: A consultation will take place to discuss your treatment goals and medical history.
Preparation: The treatment area is thoroughly disinfected. Numbing (cream) are used to provide maximum comfort during the treatment.
Injection: Once the area is prepared, the dermal filler is carefully injected beneath the skin using a fine needle or cannula. The injection process is relatively quick and usually well-tolerated. After the injections, the practitioner may massage the treated area to ensure the filler is evenly distributed. They will also assess the results and make any necessary adjustments to achieve the best result.
Post-treatment care: You may experience some mild swelling, redness, or bruising at the injection site. You will be provided with post-treatment care instructions to minimise any potential side effects and ensure the best results.
Follow-up: A follow-up can be arrange after 2 weeks to ensure best results.

Chin Filler

Refine your profile and bring balance to your features with expert chin filler at Mr. & Mrs. Fillers in Portsmouth. This non-surgical treatment enhances chin shape and projection for a more harmonious facial appearance.

Chin filler is a hyaluronic acid-based dermal filler used to improve the shape, definition, and projection of the chin. It’s a non-invasive alternative to surgery that can subtly enhance your side profile and facial proportions.

Consultation: A consultation will take place to discuss your treatment goals and medical history.
Preparation: The treatment area is thoroughly disinfected. Numbing (cream) are used to provide maximum comfort during the treatment.
Injection: Once the area is prepared, the dermal filler is carefully injected beneath the skin using a fine needle or cannula. The injection process is relatively quick and usually well-tolerated. After the injections, the practitioner may massage the treated area to ensure the filler is evenly distributed. They will also assess the results and make any necessary adjustments to achieve the best result.
Post-treatment care: You may experience some mild swelling, redness, or bruising at the injection site. You will be provided with post-treatment care instructions to minimise any potential side effects and ensure the best results.
Follow-up: A follow-up can be arrange after 2 weeks to ensure best results.

You will see the change immediately after your treatment! However, you will be able to see the final result after 2-4 weeks once the area heals and the filler settles into it's final position.

More defined, proportionate chin
Improved side profile and lower-face harmony
Results last 9–15 months, depending on lifestyle and product used
Natural, subtle enhancement
Suitable for both men and women

Liquid Rhinoplasty

Transform your nose without surgery with liquid rhinoplasty at Mr. & Mrs. Fillers in Portsmouth. This non-surgical treatment reshapes and smooths the nose using dermal filler — no downtime, no scalpel, just instant results.

Also known as a non-surgical nose job, this treatment uses hyaluronic acid dermal filler to improve the shape, symmetry, and profile of the nose. It’s ideal for smoothing bumps, lifting the tip, or straightening the nasal bridge — all without surgery.

Consultation: A consultation will take place to discuss your treatment goals and medical history.
Preparation: The treatment area is thoroughly disinfected. Numbing (cream) are used to provide maximum comfort during the treatment.
Injection: Once the area is prepared, the dermal filler is carefully injected beneath the skin using a fine needle or cannula. The injection process is relatively quick and usually well-tolerated. After the injections, the practitioner may massage the treated area to ensure the filler is evenly distributed. They will also assess the results and make any necessary adjustments to achieve the best result.
Post-treatment care: You may experience some mild swelling, redness, or bruising at the injection site. You will be provided with post-treatment care instructions to minimise any potential side effects and ensure the best results.
Follow-up: A follow-up can be arrange after 2 weeks to ensure best results.

You will see the change immediately after your treatment! However, you will be able to see the final result after 2-4 weeks once the area heals and the filler settles into it's final position.

Instant reshaping and contouring
Straighter, more refined nose profile
Completely reversible if needed
Results last 9–15 months, depending on lifestyle and product used
Natural, subtle enhancement
Suitable for both men and women

Frown Line Treatment (11’s)
Say goodbye to deep forehead lines with professional frown line treatment (11’s) at Mr. & Mrs. Fillers in Portsmouth. Using precise injections, we smooth the vertical lines between the eyebrows for a fresher, more relaxed appearance.

Frown lines — also called “11’s” — are the vertical creases that appear between the eyebrows due to repeated muscle movement. We use hyaluronic acid filler injections to soften the lines and preventing them from deepening over time.

Consultation: A consultation will take place to discuss your treatment goals and medical history.
Preparation: The treatment area is thoroughly disinfected. Numbing (cream) are used to provide maximum comfort during the treatment.
Injection: Once the area is prepared, the dermal filler is carefully injected beneath the skin using a fine needle or cannula. The injection process is relatively quick and usually well-tolerated. After the injections, the practitioner may massage the treated area to ensure the filler is evenly distributed. They will also assess the results and make any necessary adjustments to achieve the best result.
Post-treatment care: You may experience some mild swelling, redness, or bruising at the injection site. You will be provided with post-treatment care instructions to minimise any potential side effects and ensure the best results.
Follow-up: A follow-up can be arrange after 2 weeks to ensure best results.

Temple Filler
Temple filler is a hyaluronic acid-based dermal filler treatment used to correct hollow or sunken temples — a common sign of ageing. By restoring volume in this area, we soften the face, improve brow support, and create a smoother, more youthful silhouette.

temple-filler-treatment-before-after-volume-restoration-portsmouth

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Temple filler is a hyaluronic acid-based dermal filler treatment used to correct hollow or sunken temples — a common sign of ageing.

By restoring volume in this area, we soften the face, improve brow support, and create a smoother, more youthful silhouette.

Consultation: A consultation will take place to discuss your treatment goals and medical history.
Preparation: The treatment area is thoroughly disinfected. Numbing (cream) are used to provide maximum comfort during the treatment.
Injection: Once the area is prepared, the dermal filler is carefully injected beneath the skin using a fine needle or cannula. The injection process is relatively quick and usually well-tolerated. After the injections, the practitioner may massage the treated area to ensure the filler is evenly distributed. They will also assess the results and make any necessary adjustments to achieve the best result.
Post-treatment care: You may experience some mild swelling, redness, or bruising at the injection site. You will be provided with post-treatment care instructions to minimise any potential side effects and ensure the best results.
Follow-up: A follow-up can be arrange after 2 weeks to ensure best results.

You will see the change immediately after your treatment! However, you will be able to see the final result after 2-4 weeks once the area heals and the filler settles into it's final position.

Fuller, smoother temples
Lifted brow and improved facial proportions
Natural, refreshed appearance
Results last around 9–18 months
Natural, subtle enhancement
Suitable for both men and women

Anti-Wrinkle Injections

Smooth fine lines and refresh your appearance with professional anti-wrinkle injections at Mr. & Mrs. Fillers in Portsmouth. This trusted, non-surgical treatment targets dynamic wrinkles — giving you a softer, more youthful look with natural results.

Anti-wrinkle injections are designed to temporarily reduce the appearance of wrinkles and fine lines. They contain a purified protein derived from botulinum toxin that relaxes the muscles responsible for causing wrinkles, resulting in a smoother, more youthful appearance.

Other uses:

Jawline slimming - Anti-wrinkle injections can be used to create a slimmer jawline by reducing the size of the masseter muscles.

Are Anti-Wrinkle Injections Right for Me?

✔️ You have dynamic wrinkles (caused by movement)
✔️ You want a non-surgical, preventative anti-ageing solution
✔️ You’re over 18, in good health, and not pregnant or breastfeeding
✔️ You want subtle, natural-looking results
✔️ You have realistic expectations
✔️ You prefer a natural, tailored look

✔️ Suitable for both men and women

Consultation: A consultation will take place to discuss your treatment goals and medical history.
Preparation: The treatment area is thoroughly disinfected. Numbing is not typically used as the treatment is well tolerated with minimal discomfort.
Injection: The solution is injected with a fine needle into the targeted muscles beneath the skin. Mild swelling or redness may occur but will subside shortly. The practitioner will provide you with post-treatment care instructions to minimise any potential side effects and ensure the best results.
Follow-up: A follow-up appointment will be arrange after 2 weeks to assess the need for a top-up to achieve best results.

You may start to notice initial improvements within a few days after the treatment, but the full effects of the anti-wrinkle injections usually become visible within 1 to 2 weeks.

Results typically last around 3 to 4 months, after which the muscle action gradually returns, and wrinkles may begin to reappear.

Regular maintenance treatments can help prolong the desired results and reduce the formation of new wrinkles over time.

Minimal Downtime

Healing after anti-wrinkle injections is generally quick. You might experience some mild redness, swelling, or small injection-site bruises, which should subside within a couple of days.

Most people can return to normal daily activities immediately after the procedure. It's recommended to avoid vigorous exercise, alcohol consumption, and extensive sun exposure on the day of treatment.

Chemical Peel

Reveal brighter, smoother skin with a chemical peel at Mr. & Mrs. Fillers in Portsmouth. This advanced skin rejuvenation treatment targets dullness, fine lines, acne, and pigmentation — leaving your complexion refreshed and renewed.

Chemical peels are designed to enhance the appearance of the skin, particularly on the face, neck, or hands by exfoliating the surface layer of the skin, removing dead cells and stimulating collagen production..

The solution typically contains one or more acids, such as alpha hydroxy acids (AHAs), beta hydroxy acids (BHAs), or trichloroacetic acid (TCA), depending on the type and strength of the peel.

Peels can be superficial, medium, or deep — depending on your skin goals.

Are Chemical Peels Right for Me?

Our peels are suitable for all skin tones and types. They typically address moderate skin concerns, such as:

Sun Damage: They can reduce the appearance of sunspots, freckles, and pigmentation irregularities caused by excessive sun exposure.
Fine Lines and Wrinkles: They can help smooth out moderate wrinkles and fine lines, giving the skin a more youthful appearance.
Skin Texture: They are effective in reducing the appearance of acne scars and improving skin texture.
Uneven Skin Tone: They can even out skin tone and improve the skin's overall complexion.
Suitable for both men and women

Consultation: During the consultation you'll discuss your skin concerns, medical history, and goals. The most suitable peel type, strength, and duration will be selected based on your skin type and needs. You will also be advised on the skincare routine to follow on the days leading up to your peel to minimise potential side effects.
Cleansing: On the day of the treatment your skin will be thoroughly cleansed, this ensures that the chemical peel can penetrate the skin effectively.
Application of Chemical Peel: The chemical peel solution will be applied to your skin using a brush or cotton applicator. The peel solution is left on your skin for a specific amount of time, determined by the type of peel and your skin's response.
Sensation: You may experience a tingling or burning sensation as the chemical peel solution is applied. The intensity of this sensation can vary, but it's generally temporary and subsides quickly.
Neutralisation: After the desired amount of time has passed, the chemical peel will be deactivated using a neutralising solution.
Post-Treatment Care: You will be provided with post-treatment instructions, which may include applying a soothing cream, avoiding direct sunlight, and using sunscreen. It's crucial to follow these instructions to ensure proper healing and optimal results.

Skin Boosters
Achieve glowing, hydrated skin from within with skin boosters at Mr. & Mrs. Fillers in Portsmouth. This injectable treatment delivers deep hydration, improves texture, and gives your skin a radiant, refreshed appearance — without changing facial structure.

Skin boosters are injectable moisturisers made with hydrating ingredients like hyaluronic acid. They are designed to improve overall skin quality, elasticity, and smoothness by boosting hydration and stimulating collagen from within.

Are Skin Boosters Right for Me?

Skin Boosters are best suited for those with mild to moderate signs of skin aging, including fine lines, wrinkles, and skin laxity. It's also effective for those with dehydrated or dry skin, seeking overall skin quality improvement and enhanced moisture retention.

Skin Boosters are versatile and safe for various skin types, individual suitability should be assessed through a consultation.

Realistic expectations about subtle improvements are important, as Skin Boosters may not address severe signs of aging or volume loss.

Suitable for both men and women

Consultation: During this consultation, you will discuss your specific skin concerns, goals, and medical history. The practitioner will assess your skin type and determine if you are a suitable for various skin boosters.
Preparation: Your skin will be thoroughly cleansed before injections. Numbing cream is optional as the treatment is generally well tolerated.
Injections: Skin boosters are injected superficially beneath the surface of the skin using a find needle. Injection patterns may vary but usually on the face it is injected into 5 points on each side of the face.
Post-treatment care: You may experience some bee-sting-like bumps, redness, or bruising at the injection site. You will be provided with post-treatment care instructions to minimise any potential side effects and ensure the best results.

Results from skin boosters treatment typically begin with subtle improvements in skin hydration within a few days to a week after the first session.

However, the most significant changes, such as enhanced skin quality, firmness, and elasticity, become noticeable around 4 to 6 weeks following the initial treatment.

To maintain results, many individuals opt for maintenance treatments every 6 to 12 months.

Keep in mind that individual responses vary based on factors like skin type and age.

Minimal Downtime

After skin bosters treatment you may experience some minor side effects, including redness and swelling. These effects are generally temporary and should subside within a few hours to a couple of days.

Most individuals can resume the majority of their regular activities shortly after the procedure with no downtime.

It's crucial to follow the provided aftercare instructions to ensure proper healing and optimal results.

Fat Dissolving
Target stubborn pockets of fat with fat dissolving injections at Mr. & Mrs. Fillers in Portsmouth. This non-surgical treatment breaks down and eliminates localised fat that doesn’t respond to diet or exercise — helping you contour and define your shape safely and effectively.

Fat dissolving injections are used to reduce localised pockets of fat. These injections contain a substance called deoxycholic acid, which is a naturally occurring bile acid that helps the body break down and absorb dietary fat. When injected into specific areas of the body, it can target and destroy fat cells, leading to a reduction in fat volume in those areas.

Good candidates for fat dissolving injections typically meet the following criteria:

You are close to your ideal body weight, but have localised areas of unwanted fat that are resistant to diet and exercise. Common treatment areas include the double chin, abdomen, and love handles.
You have realistic expectations about the results. Fat dissolving injections are not a substitute for weight loss or a comprehensive body contouring solution. They are most effective for targeted fat reduction in specific areas.
You have a stable and healthy body weight.

Consultation: At the consultation you will discuss your specific goals, medical history, and determine if you are a suitable candidate for fat dissolving injections.
Preparation: The treatment area will be thoroughly cleansed and topical numbing cream will be applied to minimise discomfort.
Injection Process: The fat dissolved solution will be injected directly into the targeted fat deposits using a fine needle. Multiple injections will be administered in a session depending on the size and number of areas being treated.
Sensation: You may experience some discomfort, burning, or stinging at the injection sites as the solution is being injected.
Post-Treatment Care: After the injections are complete, you will be provided with post-treatment instructions. Including applying ice to the treated area, avoiding strenuous exercise and excessive sun exposure for a few days.
Follow-Up: A follow-up appointments will scheduled to assess your progress and determine if additional treatments are needed to achieve your goals.

PRP Hair Loss Treatment

Stimulate natural hair growth with PRP hair loss treatment at Mr. & Mrs. Fillers in Portsmouth. This innovative, non-surgical therapy uses your body’s own platelets to reactivate dormant hair follicles and encourage thicker, healthier hair.

Platelet-Rich Plasma (PRP) is a medical treatment used to address hair loss and promote hair regrowth. It involves the use of the patient's own blood to extract platelet-rich plasma, which is then injected into the scalp in areas experiencing hair thinning or loss.

The platelet-rich plasma contains growth factors that can stimulate hair follicles, improve blood circulation in the scalp, and promote the growth of thicker and healthier hair. It's important to note that PRP is not a one-time, instant solution for hair loss, PRP a series of sessions is required, and it is often used in conjunction with other hair restoration treatments, such as medications like minoxidil or finasteride.

Our recommendation are 6 treatments for visible results

PRP hair loss treatment can be effective for certain individuals experiencing various forms of hair loss. However, not everyone is an ideal candidate for this procedure. Here are factors that may make someone a good candidate for this treatment:

Early Stages of Hair Loss: PRP is generally more effective when used in the early stages of hair loss or when the hair follicles are still active. It may not be as effective for individuals with extensive baldness or long-standing hair loss.
Male and Female Pattern Baldness: PRP is suitable for both men and women experiencing androgenetic alopecia, commonly known as male or female pattern baldness.
Thinning Hair: PRP can be beneficial for individuals with diffuse hair thinning or areas of thinning hair, where hair follicles are still present but producing weaker or finer hair.
Good Overall Health: Candidates should be in good overall health with no underlying health conditions.

Consultation: During the consultation, you will discuss your specific hair concerns, goals, and medical history. The practitioner will assess your hair loss type and determine if you are a suitable candidate for PRP hair treatment.
Blood Draw: A small amount of your blood is drawn, usually from your arm similar to a routine blood test. This blood sample is then processed in a centrifuge machine to extract the platelet-rich plasma (PRP).
Preparation: The injection sites will be thoroughly disinfected and an optional local aesthetic may be applied to the scalp to minimise any discomfort during the injections.
PRP Injection: The PRP is injected using a fine needle directly into the scalp in the areas experiencing hair loss or thinning.
Sensation: You may experience a sensation of mild pressure or a slight burning or tingling at the injection sites, but any discomfort is typically minimal and temporary.
Post-Treatment Care: After the procedure, you will be provided with post-treatment instructions. This includes avoiding washing your hair for 12-24 hours and refraining from vigorous exercise or activities that cause excessive sweating for a day or two. You'll also be advised to avoid sun exposure to the treated areas.

The timeline for seeing results from PRP hair loss treatment can vary from person to person, and it depends on several factors, including the individual's unique response to the treatment and the extent of hair loss.

However, here's a general timeline of what you can typically expect:

Initial Results: Some individuals may notice initial improvements in hair texture and thickness within a few weeks after their first PRP session. This is often due to enhanced blood circulation in the scalp and the stimulation of dormant hair follicles.
Progressive Improvement: The most significant changes usually become visible after a series of PRP treatments. A common treatment plan involves four to six sessions spaced about 4 to 6 weeks apart. You can expect progressive improvement with each session.
Full Results: The full effects of PRP treatment for hair loss are typically visible around 3 to 6 months after the final session in a treatment series. During this time, you may notice increased hair density, reduced hair shedding, and overall improved hair quality.
Maintenance: To maintain the results achieved, top-up sessions are typically scheduled every 6 to 12 months, depending on individual needs and how well the results are sustained.

It's important to note that PRP is not a one-time, instant solution for hair loss. Patience is key, as it can take time for hair follicles to respond to the treatment and for new hair growth to become noticeable.

PRP Treatment
Rejuvenate your skin naturally with Platelet-Rich Plasma (PRP) Therapy at Mr. & Mrs. Fillers in Portsmouth. This cutting-edge, non-surgical treatment uses your own blood’s healing power to regenerate skin, improve texture, and restore a youthful glow — often referred to as the "vampire facial."

Platelet-Rich Plasma (PRP) therapy involves taking a small blood sample, processing it to concentrate your platelets (rich in growth factors), and re-injecting it into the skin. These growth factors stimulate collagen, improve circulation, and encourage cell turnover — making it a powerful treatment for dullness, fine lines, scarring, and elasticity loss.

Our recommendation are 3 treatments for visible results

Consultation: During the consultation, you will discuss your specific concerns, goals, and medical history.
Blood Draw: A small amount of your blood is drawn, usually from your arm similar to a routine blood test. This blood sample is then processed in a centrifuge machine to extract the platelet-rich plasma (PRP).
Preparation: The injection sites will be thoroughly disinfected.
PRP Injection: The PRP is injected using a fine needle directly into the target area.
Sensation: You may experience a sensation of mild pressure or a slight burning or tingling at the injection sites, but any discomfort is typically minimal and temporary.
Post-Treatment Care: After the procedure, you will be provided with post-treatment instructions. This includes avoiding refraining from vigorous exercise or activities that cause excessive sweating for a day or two. You'll also be advised to avoid sun exposure to the treated areas.
Suitable for face, neck, décolletage, or hands

Microneedling with Exosomes
Transform your skin with the future of regenerative aesthetics: microneedling with exosomes at Mr. & Mrs. Fillers, Portsmouth. This powerful treatment pairs collagen induction therapy with cell-signalling technology to dramatically improve skin texture, tone, and radiance — with minimal downtime.

Microneedling uses tiny needles to create controlled micro-injuries in the skin, triggering natural collagen and elastin production. When combined with exosomes — potent regenerative molecules derived from stem cells — it supercharges healing, boosts cell turnover, and enhances skin rejuvenation at a cellular level.

Our recommendation are 3 treatments for visible results

Consultation: During the consultation, you will discuss your specific concerns, goals, and medical history.
Preparation: The targeted site will be thoroughly disinfected.
Exosomes microneedling: The Exosomes are applied on the skin and blended with microneedling technique using fine needles directly into the target area.
Sensation: You may experience a sensation of mild burning or tingling at the injection sites, but any discomfort is typically minimal and temporary.
Post-Treatment Care: After the procedure, you will be provided with post-treatment instructions. This includes avoiding refraining from vigorous exercise or activities that cause excessive sweating for a day or two. You'll also be advised to avoid sun exposure to the treated areas.
Suitable for face, neck, décolletage, or hands
A course of 3 sessions is typically recommended for optimal results

Mild redness and tightness for 24–72 hours
Minimal flaking or dryness may occur
Avoid sun, makeup, and vigorous activity for 24–48 hours
Use gentle skincare and SPF daily post-treatment

These effects are generally temporary and should subside within a few hours to a couple of days.
Most individuals can resume the majority of their regular activities shortly after the procedure with no downtime.

Microneedling
Restore your skin’s natural glow with microneedling at Mr. & Mrs. Fillers in Portsmouth. This advanced, minimally invasive treatment boosts collagen, reduces scarring, and improves overall skin texture — for firmer, fresher, and younger-looking skin.

Microneedling

Is a non-surgical treatment that uses a device with ultra-fine, sterile needles to create tiny punctures in the skin’s surface. These controlled micro-injuries kickstart your body’s natural healing process, stimulating collagen and elastin production.

This collagen boost helps to firm, smooth, and rejuvenate the skin – making microneedling one of the most effective treatments for a range of concerns.

Top Benefits of Microneedling

Improves Skin Texture and Tone

If you’re dealing with rough or uneven skin, enlarged pores, or dullness, microneedling helps refine texture and give your skin a radiant, even glow.

Reduces Fine Lines and Wrinkles

Microneedling encourages collagen production, which naturally plumps the skin and softens the appearance of fine lines and early signs of ageing.

Fades Acne Scars and Marks

This treatment is ideal for reducing the look of acne scarring, post-inflammatory hyperpigmentation, and general textural scarring by promoting skin renewal from within.

Boosts Skincare Absorption

After microneedling, your skin is primed to absorb active ingredients more effectively – so your serums and moisturisers work even harder.

Dermaplaning
Restore your skin’s natural glow with dermaplaning at Mr. & Mrs. Fillers in Portsmouth. This advanced, minimally invasive treatment that improves overall skin texture — for firmer, fresher, and younger-looking skin.

Dermaplaning is a gentle, non-invasive exfoliation treatment designed to remove dead skin cells and fine vellus hair (also known as "peach fuzz") from the surface of the skin. Using a sterile surgical blade, the procedure smooths and brightens the complexion instantly. Dermaplaning helps to promote better skincare absorption, enhances makeup application, and leaves your skin looking ultra-glowy, soft, and refreshed. It’s safe, quick, and suitable for most skin types — including sensitive skin.

Polynucleotide Skin Treatment

This advanced regenerative treatment is the latest in aesthetic skin therapy. Whether you’re targeting early signs of ageing, dullness, or skin repair, Polynucleotide (PN) injections offer a science-backed, natural-looking boost for smoother, firmer, and healthier skin — now available at Mr. & Mrs. Fillers, Portsmouth.

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Side profile before and after showing polynucleotide facial rejuvenation for mature skin at Mrs. Fillers Aesthetics, Portsmouth.

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Visible facial transformation using polynucleotide-based anti-ageing therapy at Mrs. Fillers Aesthetics, Portsmouth. Ideal for mature skin, polynucleotides stimulate tissue repair, hydrate deeply, and smooth fine lines naturally. Leading clinic for non-surgical skin rejuvenation in Portsmouth.

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Close-up results of polynucleotide injections at Portsmouth’s trusted aesthetic clinic. Notice reduction in pigmentation, enhanced elasticity, and refined skin texture after regenerative polynucleotide therapy at Mrs. Fillers Aesthetics.

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Side profile before and after showing polynucleotide facial rejuvenation for mature skin at Mrs. Fillers Aesthetics, Portsmouth.

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Polynucleotide (PN) skin treatments are cutting-edge procedures aimed at
rejuvenating and revitalising the skin. PN therapy involves the use of nucleotides,
which are essential building blocks of DNA and RNA, to promote collagen
production, improve skin elasticity, and reduce the appearance of wrinkles and fine
lines. These treatments are safe, non-invasive, and suitable for all areas of the face
and body for individuals seeking natural-looking results.

During a PN skin treatment we will begin by thoroughly cleansing the treatment area. A topical numbing cream may be applied to ensure comfort throughout the
procedure. The PN solution is then carefully injected into the skin using fine needles or administered via cannula technique, depending on the specific treatment plan tailored to your needs. The procedure typically takes about 30 to 60 minutes, and most patients experience minimal discomfort.

Results from PN skin treatments are often noticeable within a few weeks following
the procedure, as collagen production increases and skin begins to rejuvenate.
However, optimal results are usually achieved after a series of treatments spaced
several weeks apart. The duration of results can vary depending on individual factors
such as skin type, age, and lifestyle habits. With proper skincare maintenance and
occasional touch-up treatments, results can last up to 6 to 12 months.

Our Services

Mr. & Mrs. Fillers Aesthetics – Portsmouth’s Leading Aesthetic Clinic

Anti-Ageing & Facial Rejuvenation Treatments

Dermal Fillers

Anti-Wrinkle Injections

Polynucleotide Skin Rejuvenation

Skin Boosters (Profhilo, Seventy Hyal & More)

Microneedling with or without PRP

Skin Health & Texture Improvement

Chemical Peels

PRP Therapy (Vampire Facial)

Hair Fillers​

Fat Reduction & Facial Contouring

Fat Dissolving Injections (Lemon Bottle & Aqualyx)

Temple Filler for Facial Lifting

Lip Fillers Looking for safe, natural-looking lip enhancement in Portsmouth? At Mr. & Mrs. Fillers, we offer expert lip filler treatments using premium hyaluronic acid-based products for fuller, more defined lips.

Nasolabial folds/ Smile Lines/ Marionette Lines Softening deep smile lines for a more youthful, refreshed look is easier than ever with nasolabial fold fillers at Mr. & Mrs. Fillers in Portsmouth.

Tear Through Filler Tired, hollow under-eyes? At Mr. & Mrs. Fillers in Portsmouth, we offer expert tear trough filler treatments to brighten and refresh your under-eye area, reducing dark circles and tired-looking hollows without surgery.

Cheek Filler Enhance your natural features with expertly applied cheek filler at Mr. & Mrs. Fillers in Portsmouth. This popular treatment adds lift, volume, and definition to the mid-face — helping you achieve a youthful, sculpted appearance without surgery.

Jawline Filler Define and sculpt your profile with jawline filler at Mr. & Mrs. Fillers in Portsmouth. This non-surgical treatment enhances the structure of your lower face for a sharper, more contoured appearance with natural-looking results.

Chin Filler

Refine your profile and bring balance to your features with expert chin filler at Mr. & Mrs. Fillers in Portsmouth. This non-surgical treatment enhances chin shape and projection for a more harmonious facial appearance.

Liquid Rhinoplasty

Transform your nose without surgery with liquid rhinoplasty at Mr. & Mrs. Fillers in Portsmouth. This non-surgical treatment reshapes and smooths the nose using dermal filler — no downtime, no scalpel, just instant results.

Frown Line Treatment (11’s) Say goodbye to deep forehead lines with professional frown line treatment (11’s) at Mr. & Mrs. Fillers in Portsmouth. Using precise injections, we smooth the vertical lines between the eyebrows for a fresher, more relaxed appearance.

Temple Filler Temple filler is a hyaluronic acid-based dermal filler treatment used to correct hollow or sunken temples — a common sign of ageing. By restoring volume in this area, we soften the face, improve brow support, and create a smoother, more youthful silhouette.

Anti-Wrinkle Injections

Smooth fine lines and refresh your appearance with professional anti-wrinkle injections at Mr. & Mrs. Fillers in Portsmouth. This trusted, non-surgical treatment targets dynamic wrinkles — giving you a softer, more youthful look with natural results.

Chemical Peel

Reveal brighter, smoother skin with a chemical peel at Mr. & Mrs. Fillers in Portsmouth. This advanced skin rejuvenation treatment targets dullness, fine lines, acne, and pigmentation — leaving your complexion refreshed and renewed.

Skin Boosters Achieve glowing, hydrated skin from within with skin boosters at Mr. & Mrs. Fillers in Portsmouth. This injectable treatment delivers deep hydration, improves texture, and gives your skin a radiant, refreshed appearance — without changing facial structure.

Fat Dissolving Target stubborn pockets of fat with fat dissolving injections at Mr. & Mrs. Fillers in Portsmouth. This non-surgical treatment breaks down and eliminates localised fat that doesn’t respond to diet or exercise — helping you contour and define your shape safely and effectively.

PRP Hair Loss Treatment

Stimulate natural hair growth with PRP hair loss treatment at Mr. & Mrs. Fillers in Portsmouth. This innovative, non-surgical therapy uses your body’s own platelets to reactivate dormant hair follicles and encourage thicker, healthier hair.

Microneedling Restore your skin’s natural glow with microneedling at Mr. & Mrs. Fillers in Portsmouth. This advanced, minimally invasive treatment boosts collagen, reduces scarring, and improves overall skin texture — for firmer, fresher, and younger-looking skin.

Microneedling

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Dermaplaning Restore your skin’s natural glow with dermaplaning at Mr. & Mrs. Fillers in Portsmouth. This advanced, minimally invasive treatment that improves overall skin texture — for firmer, fresher, and younger-looking skin.

Polynucleotide Skin Treatment

Hair Fillers

Lip Fillers
Looking for safe, natural-looking lip enhancement in Portsmouth?
At Mr. & Mrs. Fillers, we offer expert lip filler treatments using premium hyaluronic acid-based products for fuller, more defined lips.

Nasolabial folds/ Smile Lines/ Marionette Lines
Softening deep smile lines for a more youthful, refreshed look is easier than ever with nasolabial fold fillers at Mr. & Mrs. Fillers in Portsmouth.

Tear Through Filler
Tired, hollow under-eyes? At Mr. & Mrs. Fillers in Portsmouth, we offer expert tear trough filler treatments to brighten and refresh your under-eye area, reducing dark circles and tired-looking hollows without surgery.

Cheek Filler
Enhance your natural features with expertly applied cheek filler at Mr. & Mrs. Fillers in Portsmouth. This popular treatment adds lift, volume, and definition to the mid-face — helping you achieve a youthful, sculpted appearance without surgery.

Jawline Filler
Define and sculpt your profile with jawline filler at Mr. & Mrs. Fillers in Portsmouth. This non-surgical treatment enhances the structure of your lower face for a sharper, more contoured appearance with natural-looking results.

Frown Line Treatment (11’s)
Say goodbye to deep forehead lines with professional frown line treatment (11’s) at Mr. & Mrs. Fillers in Portsmouth. Using precise injections, we smooth the vertical lines between the eyebrows for a fresher, more relaxed appearance.

Temple Filler
Temple filler is a hyaluronic acid-based dermal filler treatment used to correct hollow or sunken temples — a common sign of ageing. By restoring volume in this area, we soften the face, improve brow support, and create a smoother, more youthful silhouette.

Skin Boosters
Achieve glowing, hydrated skin from within with skin boosters at Mr. & Mrs. Fillers in Portsmouth. This injectable treatment delivers deep hydration, improves texture, and gives your skin a radiant, refreshed appearance — without changing facial structure.

Fat Dissolving
Target stubborn pockets of fat with fat dissolving injections at Mr. & Mrs. Fillers in Portsmouth. This non-surgical treatment breaks down and eliminates localised fat that doesn’t respond to diet or exercise — helping you contour and define your shape safely and effectively.

Microneedling
Restore your skin’s natural glow with microneedling at Mr. & Mrs. Fillers in Portsmouth. This advanced, minimally invasive treatment boosts collagen, reduces scarring, and improves overall skin texture — for firmer, fresher, and younger-looking skin.

Dermaplaning
Restore your skin’s natural glow with dermaplaning at Mr. & Mrs. Fillers in Portsmouth. This advanced, minimally invasive treatment that improves overall skin texture — for firmer, fresher, and younger-looking skin.